KIC is another very important nutrient capable of producing significant anabolic effects. KIC is the branched chain keto acid of leucine, and it occurs naturally in muscle and liver metabolism. Unlike leucine, however, dietary KIC affects the liver to greater extent than muscle tissue. Eighty percent of dietary KIC’s are taken up by the liver, where it decreases the catabolism of amino acids.
The immediate obvious effect of dietary KIC that it reduces urine-urea nitrogen and increases nitrogen retention, the long term effect which could result in increased muscle mass