OKG may provide significant relief during periods of illness by protecting stores of muscle protein. This is because of OKG’s effects on intramuscular glutimine stores. The loss o intermuscular stores of glutimine during trama, illness or stress leads to an increase in muscle-protein degradation. Subsequent to a variety of stressors, which include caloric restriction, glutimine is released from the muscle to support the metabolism of tissues such as the gastrointestinal tract and immune system.
The Alpha-Ketoglutarate portion of OKG provides the carbon skeleton for glutimine synthesis, while it is still believed that ornithine slows the production of urea, resulting in higher and more stable serum levels of glutimine.
Because maintenance of immune function is dependent on glutimine, adequate serum levels of glutimine are important for optimal immune response and timely recovery. Consequently, taking gram amounts of OKG during illness not only limits muscle wasting but also supports immune response, facilitating a quicker recovery.
OKG may be helpful in conditions of over training as well. Over training can readily occur after moths of relentless workouts. The importance of adequate nutrition and stress reduction in limiting the loss of body weight as well as injury can not be understated. Adding recommended maintenance amounts of OKG to a bodybuilders diet may go a long way to stabilizing muscle mass and limiting injuries linked to loss of strength and body weight.